NQO1 is a multifaceted enzyme involved in various cellular processes, including detoxification, redox regulation, and metabolic pathways, making it crucial for overall cellular health and disease prevention
NQO1 is a versatile enzyme with multiple roles in cellular health. While initially known for its detoxifying properties, recent research has revealed its broader functions. NQO1 not only metabolizes quinones but also influences NAD+ levels, protein synthesis, and protein stability. Additionally, it plays a crucial role in the plasma membrane redox system, contributing to antioxidant defense. Interestingly, NQO1’s activity can be regulated by cellular redox state, suggesting its potential role as a redox sensor. Understanding the complex functions of NQO1 provides valuable insights into its significance in oxidative stress related diseases.
