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Oxidative Stress: Harms and Benefits for Human Health

Oxidative Stress: Harms and Benefits: Oxidative stress is a phenomenon caused by an imbalance of oxygen reactive species (ROS) in cells and tissues. ROS play several physiological roles (i.e., cell signaling), and they are normally generated as by-product of oxygen metabolism; despite this, environmental stressors (i.e., UV, ionizing radiations, pollutants, and heavy metals) contribute to […]

Oxidative Stress: Harms and Benefits for Human Health

Oxidative Stress: Harms and Benefits: Oxidative stress is a phenomenon caused by an imbalance of oxygen reactive species (ROS) in cells and tissues. ROS play several physiological roles (i.e., cell signaling), and they are normally generated as by-product of oxygen metabolism; despite this, environmental stressors (i.e., UV, ionizing radiations, pollutants, and heavy metals) contribute to […]

Short Overview of ROS as Cell Function Regulators and Their Implications in Therapy Concepts.

It is important to maintain a balanced redox mediator environment for optimal cellular functioning as a potential therapeutic target for healing and regeneration. Reactive oxygen species (ROS) are molecules generated during normal cellular processes that can act as regulators of cellular functions. ROS play a dual role in affecting cell function and acting as mediators […]

Hydrogen peroxide as a signal for skeletal muscle adaptations to exercise: What do concentrations tell us about potential mechanisms?

Hydrogen peroxide plays a crucial role in cell signaling, triggering positive changes in muscle strength and endurance during exercise.   Hydrogen peroxide helps send signals for various processes, such as making our muscles stronger and more efficient during exercise. When we exercise, our muscles undergo positive changes like increased strength and endurance that are triggered by […]

Redox Theory of Aging

The theory of aging states that aging is the decline of the body’s interconnected redox-dependent systems.     The article Redox Theory of Aging explains that aging is a decline in the interaction between the genome, environmental exposures, and responses of an organism. In this manner, oxidative stress and the imbalance of cellular redox reactions contribute significantly to an […]

Epigenetics and Aging

Environmental factors such as stress and diet can impact our epigenome, which in turn affects the aging process.  Epigenetic changes play a significant role in the aging process affecting various aspects of our genome. These changes alter the accessibility of genetic material, leading to disease and decreasing longevity. Lifespan is largely influenced by epigenetic factors rather […]

Telomeres and age-related disease: how telomere biology informs clinical paradigms

Understanding how telomeres work and their impact on our cells’ health has the potential to revolutionize medical practices. Telomeres, a structure involved in protecting the ends of chromosomes, have become crucial in understanding age-related disorders. With recent advancements in science, researchers have been developing new treatments for varying conditions related to telomere length. Researchers use telomere length […]