Mitochondrial and Metabolic Dysfunction in Aging and Age-Related Diseases
Wellness Begins at the Mitochondrial Level Aging is closely tied to mitochondrial decline, which weakens energy production, raises oxidative stress,…
Category: Redox Reactions
The Gold Compound Auranofin Induces Apoptosis of Human Multiple Myeloma
Auranofin shows promise as a novel anticancer agent by inhibiting key survival pathways This research found that Auranofin (AF) induces…
The Diverse Functionality of NQO1 and its Roles in Redox Control
NQO1 is a multifaceted enzyme with roles in cellular defense, redox regulation, and various metabolic processes. Its ability to respond…
Roles of NAD(P)H: Quinone Oxidoreductase 1 in Diverse Diseases
NQO1 is a multifaceted enzyme involved in various cellular processes, including detoxification, redox regulation, and metabolic pathways, making it crucial…
Type 2 Diabetes as a Redox Disease
Metformin and exercise have opposing redox physiological roles in type 2 diabetes disease Exercise is known to be beneficial for…
Activation of Nrf2-Mediated Oxidative Stress Response in Macrophages by Hypochlorous Acid
Redox signaling molecules have been shown to activate gene pathways which respond to and protect cells from oxidation Our cells…
The Role of Nrf2 in Pulmonary Fibrosis
Nrf2 as a Molecular Weapon for Pulmonary Fibrosis Disease Pulmonary fibrosis is a lung disease and a global health issue.…