ROS Function in Redox Signaling and Oxidative Stress
Reactive Oxygen Species once seen as harmful, now seem to play a dual role in redox biology, implicated in inflammatory…
Hormesis Defines the Limits of Lifespan
Aging is Connected to an Oxidant/Antioxidant Imbalance Leading to Inflammation and Cellular Damage. Organisms Can Adapt to Stress Through a…
Sirtuins and Redox Signaling Interplay in Neurogenesis, Neurodegenerative Diseases, and Neural Cell Reprogramming
Sirtuins – The Guardians of Youthful Minds and Stem Cells, Leading the Way for Healthier Brains and Promising Discoveries in…
The Role of Nrf2 in Pulmonary Fibrosis
Nrf2 as a Molecular Weapon for Pulmonary Fibrosis Disease Pulmonary fibrosis is a lung disease and a global health issue.…
Transcription factor Nrf2 as a potential therapeutic target for COVID-19
Researchers Are Studying Whether Nrf2 Activators Could Be Used To Treat Viral Infections Such as COVID-19 Nrf2, or nuclear factor…
Dissecting the Crosstalk Between Nrf2 and NF-κB Response Pathways in Drug-Induced Toxicity
Manipulating Nrf2 and NF-κB Signaling: A Promising Frontier for Safeguarding Against Drug-Induced Toxicity. Many drugs, like overuse of APAP (Acetaminophen)…
Redox regulation, gene expression and longevity
Mild oxidative stress may not be a factor limiting longevity. Changes in genetics and the environment can make organisms like…
NRF2, a Transcription Factor for Stress Response and Beyond
NRF2 plays a vital role in controlling a complex network of functions. Ranging from how our cells process food for…
Oxidative Stress: Harms and Benefits for Human Health
Oxidative Stress: Harms and Benefits: Oxidative stress is a phenomenon caused by an imbalance of oxygen reactive species (ROS) in…
Short Overview of ROS as Cell Function Regulators and Their Implications in Therapy Concepts.
It is important to maintain a balanced redox mediator environment for optimal cellular functioning as a potential therapeutic target for…