Redox Signaling and Skeletal Muscle Adaptation during Aerobic Exercise

Redox regulation has a major role in muscle adaptation during exercise

Redox regulation is crucial for how our bodies use oxygen to produce energy, especially in muscles, where this process is essential. Studies highlight that reactive oxygen and nitrogen species (RONS) play a key role in signaling muscle adaptation during exercise. Understanding these signals has been a major focus of scientific research. This review aims to explain how RONS activate specific pathways in muscles that lead to adaptation, such as creating more energy-producing mitochondria, remodeling muscles, forming new blood vessels, regenerating nerves, and the impact of external antioxidants on these processes.

https://pubmed.ncbi.nlm.nih.gov/38650987/