NQO1 is a defensive enzyme that safeguards cells from oxidative stress, particularly in cancer. It works by neutralizing harmful compounds and protecting DNA, making it a potential target for cancer therapies
NQO1 is a protective enzyme that plays a crucial role in combating oxidative stress, particularly in cancer cells. It works by neutralizing harmful compounds and protecting DNA from damage. By reducing quinone derivatives, NQO1 can induce cell death in cancer cells. Interestingly, NQO1 expression is often elevated in tumor cells compared to normal cells. Understanding the mechanisms of NQO1 function and its potential as a therapeutic target is a promising area of cancer research. This review explores the structure, function, and clinical significance of NQO1, highlighting its potential to inhibit cancer cell growth and development.
