Short Overview of ROS as Cell Function Regulators and Their Implications in Therapy Concepts.

It is important to maintain a balanced redox mediator environment for optimal cellular functioning as a potential therapeutic target for healing and regeneration.

Reactive oxygen species (ROS) are molecules generated during normal cellular processes that can act as regulators of cellular functions. ROS play a dual role in affecting cell function and acting as mediators in various biological pathways. It is crucial to maintaining a balance in ROS levels within cells, as excessive ROS production can lead to oxidative stress and damage to cellular components. Controlled, and localized ROS generation is essential for normal cellular processes, including cell proliferation, differentiation, apoptosis, immune responses, and others. Therapeutic strategies can modulate ROS levels to achieve desired outcomes. For example, some therapies aim to enhance ROS production in cancer cells to induce selective cytotoxicity. Conversely, antioxidant-based therapies target excessive ROS levels to alleviate oxidative stress-related diseases and inflammation. Targeting ROS signaling pathways may hold promise for developing novel immunotherapies. Overall, the article underscores the complex and intricate role of ROS as cell function regulators. Understanding the mechanisms by which ROS influence cellular processes can lead to the development of innovative therapeutic approaches for various diseases.

https://www.mdpi.com/2073-4409/8/8/793

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