Tiny Messengers, Big Impact: How Vesicles Rewrite the Rules of Oxidative Stress
This article reviews how extracellular vesicles (EVs)—tiny particles released by cells—help regulate oxidative stress in the body through epigenetic mechanisms. These vesicles carry molecules that can influence how genes are turned on or off without changing the DNA itself. The review found that EVs can reduce harmful molecules called reactive oxygen species, increase protective antioxidants and lower markers related to cell damage. This review also highlights that while EVs show great promise for treating diseases linked to oxidative stress—like aging, cancer, and heart disease—there are still challenges. The authors call for more consistent research practices and deeper exploration into how EVs influence gene activity. Overall, the article suggests that EVs could become powerful tools in medicine, especially for conditions where managing oxidative stress is key.
