Therapeutic Potential of Alpha-Lipoic Acid: Unraveling Its Role in Oxidative Stress and Inflammatory Conditions

ALA Unleashed: A Natural Ally in the Battle Against the Aging Process

This article reviews the therapeutic potential of alpha-lipoic acid (ALA), a naturally occurring compound known for its strong antioxidant and anti-inflammatory effects. ALA helps to neutralize harmful molecules called reactive oxygen species (ROS), regenerate other antioxidants and chelates toxic metals. These properties make it especially useful in treating diseases linked to oxidative stress and inflammation related to aging.

The article highlights that ALA is effective because it can work in both water- and fat-based environments, allowing it to protect cells throughout the body. It crosses the blood-brain barrier, making it useful for brain-related conditions, and it enhances the activity of other antioxidants. Clinical and experimental studies show that ALA can reduce inflammation, improve mitochondrial function, and protect against cellular damage. The authors suggest that ALA’s wide-ranging effects and safety profile make it a promising supplement or therapeutic agent for managing chronic diseases driven by oxidative stress and inflammation.

https://www.mdpi.com/1467-3045/47/5/322