ROS Function in Redox Signaling and Oxidative Stress

Reactive Oxygen Species once seen as harmful, now seem to play a dual role in redox biology, implicated in inflammatory disease but also crucial for normal functions.

Reactive Oxygen species (ROS) were initially thought to be harmful molecules causing damage. On the other hand, they also play a beneficial role in controlling important cellular signaling pathways. New research has shown ROS levels and its location in the cell determine the fate of ROS. It is proposed that redox signaling, not oxidative stress, regulates pathways related to diseases like cancer, autoimmune, and aging. It also suggests that harnessing the power of ROS may selectively target molecules in our cells for therapy without affecting healthy tissue.